研究室工作Our Work

Taipei Medical University Clinical Research Database (TMUCRD) – A Collaborative Hospital EHR Database Aligned with International Common Data Standards

Nguyen, P.A.; Hsu, M.H.; Chang, T.H.; Yang, H.C.E.; Huang, C.W.; Liao, C.T.; Lu, C.Y.; Hsu, Jason C.* (2024/05), BMJ Health & Care Informatics [SCI]

Cost-Effectiveness Analysis of Granulocyte Colony-Stimulating Factors for the Prophylaxis of Chemotherapy-Induced Febrile Neutropenia in Patients with Breast Cancer in Taiwan

Tseng, T.H.; Chiang, S.C.; Hsu, J.C.; Ko, Y.* (2024/05), PLOS One [SCI]

Unveiling the Future of COVID-19 Patient Care: Groundbreaking Prediction Models for Severe Outcomes or Mortality in Hospitalized Cases

Hien, N.T.K.; Tsai1, F.J.; Chang, Y.H.; Burton, W.; Phuc, P.T. et al. (2024/01), Frontiers in Medicine, (in press) [SCI] (IF: 5.058)

Anti-osteoporosis Drugs Reduce Mortality in Cancer Patients: A National Cohort Study of Elderly with Vertebral Fractures

Huang, C.F.; Kuo, T.T.; Hsu, J.C.*; Kosik, R.O.; Chan, W.P.* (2023/10), Annals, Academy of Medicine, Singapore (in press) [SCI] (IF: 5.2)

Near infrared imaging system for preventing blood vision obstruction in endoscopy

Wu, M.H.#; Hsu, J.C.#; Kim, J.S.; Huang, T.J.; Huang, Y.H.; Yiu, H.P.; Lee, C.Y.; Tani, J.*; Chang, C.C.* (2023/11) Optics Express, (in press) [SCI]

Ranitidine use and incident cancer in a multinational cohort

You, S.C.; Seo, S.I.; Falconer, T. et al. (2023/09) “Ranitidine use and incident cancer in a multinational cohort”, JAMA Network Open, 2023 Sep 5;6(9):e2333495. [SCI] (IF: 13.353)

A novel prediction model of the risk of pancreatic cancer among diabetes patients using multiple clinical data and machine learning

Chen, S.M.; Phuc, P.T.; Nguyen, P.A.; Lin, S.J.; Lin, W.C.; Lu, C.Y.; Hsu, M.H.; Cheng, C.T.; Hsu, J.C.* (2023/08) , Cancer Medicine, (in press) [SCI] (IF: 4.711)

Prescription patterns of granulocyte colony–stimulating factors in patients with breast cancer: a real-world study

Hsu, S.W.; Chiang, S.C.; Hsu, J.C. (2023/07) PLOS One, (in press) [SCI]

Machine Learning and Deep Learning Approaches for Predicting 5-year Survival of Patients with Breast Cancer

Quynh, N.T.N.; Wang, C.J.; Nguyen, P.A.; Phuc, P.T.; Lin, R.K.; Hung, C.S.; Kuo, N.H.; Cheng, Y.W.; Cheng, C.T.; Hsu, M.H.*; Hsu, J.C.* (2023/07) Cancer Science (in press) [SCI] (IF: 6.518)

Age and gender differences in misperceptions of body shape in a Taiwanese population

Weng, H.C.; Chang, S.M.; Hsu, J.C.; Yang, Y.N.; Lin, C.Y. (2023/06) Journal of Eating Disorders, (in press) [SCI] (IF: 4.916)

Emotion recognition in doctor-patient interactions from real-world clinical video database: Initial development of artificial empathy

Huang, C. W., Wu, B. C. Y., Nguyen, P. A., Wang, H. H., Kao, C. C., Lee, P. C., Rahmanti, A. R., Hsu, J. C., Yang, H. C. & Li, Y. C. J. (2023/05) Computer Methods and Programs in Biomedicine. 233, 10

Comparison of local ablative therapies, including radiofrequency ablation, microwave ablation, stereotactic ablative radiotherapy, and particle radiotherapy, for inoperable hepatocellular carcinoma: A

Lee, H.L.; Cheng, P.L.; Wu, P.H.; Kao, W.Y.; Lai, Y.T.; Hsu, J.C.; Chiou, J.F.; Wu, M.H. (2023/03) Experimental Hematology & Oncology [SCI] (IF: 8.593)

Advantages of DES over BMS in preventing the risk of myocardial infarction, ischemic stroke and mortality in various populations

Wu, P.N.; Chen, J.H.; Yang, C.P.; Hsu, J.C.* (2023/1), Journal of Clinical Medicine, 12(1), 24; https://doi.org/10.3390/jcm12010024 [SCI]

Comparison Between Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression and Other Decompression Approaches for Lumbar Spinal Stenosis: A Systematic Review

Chiang, P.L.; Chen, Y.Y.; Chen, K.T.; Hsu, J.C.; Wu, C.; Lee, C.Y.; Huang, T.J.; Huang, Y.H.; Chen, C.M.; Wu, M.H.* (2022/12) , World Neurosurgery, 168, 369-380. [SCI]

Association Between Proton Pump Inhibitor Use and the Risk of Female

Nguyen, N.T.H.; Huang, C.W.; Wang, C.H.; Lin, M.C.; Hsu, J.C.; Hsu, M.H.; Iqbal, U.; Nguyen, P.-A. Yang, H.C.* (2022/12), Cancers, (in press) [SCI] (IF: 6.575)

Evidence on the Utility and Limitations to Using AI for Personalized Drug Safety Prediction

Hsu, J.C.; Lu, C.Y. (2022/12) In: Encyclopedia of Evidence in Pharmaceutical Public Health and Health Services Research in Pharmacy. Springer, Cham. https://doi.org/10.1007/978-3-030-50247-8_99-1

Development and Validation of Novel Deep-Learning Models using Multiple Data Types for Lung Cancer Survival

Hsu, J.C.; Nguyen, P.-A.; Phuc, P.T.; Lo, T.C.; Hsu, M.H.; Hsieh, M.S.; Le, N.Q.K.; Cheng, C.T.; Chang, T.H.*; Chen, C.Y.* (2022/11) , Cancers, 14, 5562. https://doi.org/10.3390/cancers14225562 [SCI]

Comparison of long-term outcomes of spinal fusion surgeries supplemented with “topping-off” implants in lumbar degenerative diseases: a systematic review and network meta-analysis

Chiou, K.; Chiu, Y.C.; Lee, C.Y.; Huang, T.J.; Lai, Y.C.; Yang, C.J.; Hsu, J.C.*; Wu, M.H.* (2022/10), North American Spine Society Journal, 12:100177. doi: 10.1016/j.xnsj.2022.100177. eCollection 202

Effectiveness and safety of immunosuppressants and biological therapy for chronic spontaneous urticaria: a network meta-analysis

Lin, W.K.; Lin, S.J.; Lee, W.R.; Lin, C.C.; Lin, W.C.; Chang, H.C.; Cheng, C.T.; Hsu, J.C.* (2022/09) , Biomedicines, 10(9):2152. doi: 10.3390/biomedicines10092152. [SCI]

Reduced all-cause mortality with bisphosphonates among post-fracture osteoporosis patients: a nationwide study and systematic review

Hsu, Y.H.; Li, C.C.; Liang, F.W.; Peng, Z.Y.; Chang, Y.F.; Hsu, J.C.; Ou, H.T.; Wu, C.H.* (2022/09), Clinical Pharmacology & Therapeutics, 112(3):711-719. doi: 10.1002/cpt.2645. Epub 2022 Jun 4. [SCI]

Determinants of COVID-19 infection by artificial intelligence technology: a study of 28 countries

Peng, H.Y.; Lin, Y.K.; Nguyen, P.A.; Hsu, J.C.*; Chou, C.L.; Chang, C.C.; Lin, C.C.; Lam, C.; Chen, C.I.; Wang, K.H.; Lu, C.Y. (2022/08), PLOS One, 17(8):e0272546. [SCI]

The impact of various anti-osteoporosis drugs on all-cause mortality after hip fractures: A nationwide population study

Tai, T.W.; Hwang, J.S.; Li, C.C.; Hsu, J.C.; Chang, C.W.; Wu, C.H.* (2022/08) , Journal of Bone and Mineral Research, 37(8):1520-1526. doi: 10.1002/jbmr.4627. Epub 2022 Jun 25. [SCI] (IF: 6.390)

Evidence on the Utility and Limitations of Artificial Intelligence for Predicting Personalized Disease Prognosis and Treatment Decisions

Hsu, J.C.; Lu, C.Y. (2022/08)In: Encyclopedia of Evidence in Pharmaceutical Public Health and Health Services Research in Pharmacy. Springer, Cham. https://doi.org/10.1007/978-3-030-50247-8_98-1

Association of Air Pollution and Weather Factors with Traffic Injury Severity: A Study in Taiwan

Ta-Chien Chan; Chih-Wei Pai; Chia-Chieh Wu; Jason C. Hsu; Ray-Jade Chen; Wen-Ta Chiu; Carlos Lam* (2022/06), International Journal of Environmental Research and Public Health [SCI]

Reduced all-cause mortality with bisphosphonates among post-fracture osteoporosis patients: a nationwide study and systematic review

Hsu, Y.H.; Li, C.C.; Liang, F.W.; Peng, Z.Y.; Chang, Y.F.; Hsu, J.C.; Ou, H.T.; Wu, C.H.* (2022/05), Clinical Pharmacology & Therapeutics, accepted, in press [SCI]

Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort

Lu, Y.*; Zandt, M.V.; Liu, Y.; Li, J.; Wang, X.; Chen, Y.; Chen, Z.; Cho, J.; Dorajoo, S.R.; Feng, M.; Hsu, M.H.; Hsu, J.C. et al. (2022/03), JAMA Network Open, 5(3):e223877 [SCI]

The association between osteoporosis medications and lowered all-cause mortality after hip or vertebral fracture in older and oldest-old adults: A nationwide population-based study

Li, C.C.#; Hsu, J.C.#; Liang, F.W.; Chang, Y.F.; Chiu, C.J.*; Wu, C.H.* (2022/03), Aging, in press [SCI]

Assessing Knowledge and Attitude of Healthcare Professionals on Biosimilars: A National Survey for Pharmacists and Physicians in Taiwan

Poon, S.Y.K.; Hsu, J.C.; Ko, Y.; Chiang, S.C.* (2021/11) , Healthcare, 9, 1600. [SCI]

Botulinum Toxin Injections for Treatment of Drooling in Children with Cerebral Palsy: A Systematic Review and Meta-analysis

Hung, S.A.; Liao, C.L.; Lin, W.P.; Hsu, J.C.; Guo, Y.H.; Lin, Y.C.* (2021/11), Children, 8, 1089. https://doi.org/10.3390/children8121089. [SCI]

雙磷酸鹽類藥物使用對骨鬆骨折病人死亡率的影響-健保資料庫分析

許育煊;李佳純;梁富文;張尹凡;徐之昇*;吳至行* (2021/09) ,台灣家庭醫學雜誌,31(3): 199-213.

Association of Social Media with Cancer Screening Awareness and Behavior for People without a Cancer Diagnosis: Matched Cohort Study

Qin, L.; Zhang, X.; Wu, A.; Miser, J.S.; Liu, Y.L.; Hsu, J.C.; Shia, B.C.; Ye, L. (2021/08), Journal of Medical Internet Research, 23(8):e26395. doi: 10.2196/26395. [SCI]

Public Awareness as a Line of Defense against COVID-19 in Taiwan

Tseng, P.; Tsai, F.J.; Hsu, J.C.; Chang, Y.C.; Wang, K.H.; Wu, M.K.; Chen, M.; Su, C.H.; Shia, B.C.; Miser, J.S. (2021/07), Asia Pacific Journal of Public Health, 10105395211030126

The Effectiveness and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer Patients with Stage III/IV: A multicenter study

Hsu, J.C.*; Nguyen, P.A.; Chen, Y.T.; Yang, S.C.; Lin, C.C.; Yang, Y.H.; Lin, Y.C.; Hsia, T.C.; Hsieh, H.C.; Wu, J.S.; Chang, C.P.; Feng, Y.H.; Lin, P.C. et al. (2021/07), , Frontiers in Oncology, (in

A cost-utility analysis of avelumab for metastatic Merkel cell carcinoma in Taiwan

Chang, W.C.; Lin, A.Y.; Hsu, J.C.; Wu, C.E.; Goh, C.; Chou, P.; Kuo, K.; Chang, A.; Palencia, R. (2021/05), Cancer Reports, e1399. doi: 10.1002/cnr2.1399. Online ahead of print.

A Real-World Observational Study of Drug Utilization and Clinical Outcomes of Direct-acting Antivirals and Interferon Therapy for Hepatitis C Treatment in Taiwan

Chen, J.H.; Wu, P.N.; Huang, S.C.; Hsu, P.J.; Hsu, J.C.* (2021/02)Current Medical Research and Opinion, 37(2): 245-252. doi: 10.1080/03007995.2020.1857716. [SCI]

Health Inequality: A Longitudinal Study on Geographic Variations in Lung Cancer Incidence and Mortality in Taiwan

Hsu, J.C.*; Tseng, Y.C.; Chang, S.M.; Lee, Y.C.; Lin, P.C.; Chu, H.J. (2020/6), BMC Public Health, 20(1): 951. [SCI]

Lung Cancer Survival and Mortality in Taiwan following the Initial Launch of Targeted Therapies: An Interrupted Time Series Study

Hsu, J.C.*; Wei, C.F.; Yang, S.C.; Lin, P.C.; Lee, Y.C.; Lu, C.Y. (2020/05), BMJ Open. May 10;10(5):e033427. doi: 10.1136/bmjopen-2019-033427. [SCI]

Comparative effectiveness and cost-effectiveness of three first-line EGFR-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan

Yang, S.C.; Lai, W.W.; Hsu, J.C.; Su, W.C.; Wang, J.D.* (2020/04) , PLOS One, 15(4):e0231413. doi: 10.1371/journal.pone.0231413. eCollection 2020. [SCI]

Comprehensive Value Assessment of Drugs using a Multi-Criteria Decision Analysis: An Example of Targeted Therapies for Metastatic Colorectal Cancer Treatment

Hsu, J.C.*; Lin, J.Y.; Lin, P.C.; Lee, Y.C. (2019/12) , PLOS One, 14(12):e0225938. doi: 10.1371/journal.pone.0225938. eCollection 2019. [SCI]

Budget Impact Analysis of Osteoporosis Medications for Primary Prevention of Fractures in Taiwan

Wu, K.L.; Wu, C.H.; Chang, Y.F.; Lin, Y.T.; Hsu, J.C.* (2019/11) , Journal of Bone and Mineral Metabolism. doi: 10.1007/s00774-019-01061-5. [SCI]

Effects of Removing Reimbursement Restrictions on Targeted Therapy Accessibility for Non-small Cell Lung Cancer Treatment in Taiwan: an Interrupted Time Series Study

Hsu, J.C.*; Wei, C.F.; Yang, S.C. (2019/03), BMJ Open, 9:e022293. doi:10.1136/bmjopen-2018-022293[SCI]

Replacement Effects and Budget Impacts of Insurance Coverage for Sodium-glucose Cotransporter-2 Inhibitors on Oral Antidiabetic Drug Utilization

Chen, H.Y.; Chiu, P.Y.; Chang, C.J.; Tsao, L.L.; Huang, Y.L.; Hsu, J.C.* (2018/12) , Clinical Drug Investigation. doi: 10.1007/s40261-018-0689-2. [SCI]

Use of Assisted Reproductive Technologies before and after the Artificial Reproduction Act in Taiwan

Hsu, J.C.*; Su, Y.C.; Tang, B.Y.; Lu, C.Y. (2018/11), PLOS One. 13(11):e0206208. doi: 10.1371/journal.pone.0206208. eCollection 2018. [SCI]

Disease and Economic Burden for Rare Diseases in Taiwan: A Longitudinal Study Using Taiwan’s National Health Insurance Research Database

Hsu, J.C.*; Wu, H.C.; Feng, W.C.; Chou, C.H.; Lai, E.C.C.; Lu C.Y. (2018/09), PLOS One. 13(9):e0204206. doi: 10.1371/journal.pone.0204206. eCollection [SCI]

Effectiveness and Safety of Immune Checkpoint Inhibitors: A Retrospective Study in Taiwan

Hsu, J.C.*; Lin, J.Y.; Hsu, M.Y.; Lin, P.C. (2018/08), PLOS One. 13(8):e0202725. doi: 10.1371/journal.pone.0202725. eCollection [SCI]

Geographic Variations and Time Trends in Cancer Treatments in Taiwan

Hsu, J.C.*; Chang, S.M.; Lu, C.Y. (2017/08), BMC Public Health, 18(1):89. doi: 10.1186/s12889-017-4615-y. [SCI]

10-year trends in statin utilization in Taiwan: a retrospective study using Taiwan’s National Health Insurance Research Database

Hsieh, H.C.; Hsu, J.C.*; Lu, C.Y. (2017/05), BMJ Open, 7(5): e014150. [SCI]

Trend and Geographic Analysis of Prevalence of Dengue in Taiwan (2010-2015)

Hsu, J.C.*; Hsieh, C.L.; Lu, C.Y. (2017/01), International Journal of Infectious Diseases, 54(1): 43-49. [SCI]

Longitudinal Trends in Use and Costs of Targeted Therapies for Common Cancers in Taiwan: A Retrospective Observational Study

Hsu, J.C.*; Lu, C.Y. (2016/06) , BMJ Open, 6(6):e011322. [SCI]

Longitudinal Trends in Targeted Therapies Use for Treatment of Malignant Neoplasms of The Eye: A Population-based Study in Taiwan

Hsu, J.C.*; Gonzalez-Gonzalez, LA.; Lu, V.H.; Lu, C.Y. (2016/05), BMJ Open, 6(5):e010706. [SCI]

Effects of Safety Warnings and Risk Management Plan for Thiazolidinediones in Taiwan

Hsu, J.C.; Cheng, C.L.; Ross-Degnan, D.; Wagner, A.K.; Zhang, F.; Kao Yang, Y.H.*; Liu, L.L.; Tai, H.Y.; Chen, K.H.; Yang, P.W.; Lu, C.Y. (2015/10) , Pharmacoepidemiology and Drug Safety, 24(10): 1026

How did Multiple FDA Actions Affect the Utilization and Reimbursed Costs of Thiazolidinediones in US Medicaid?

Hsu, J.C.*; Ross-Degnan, D.; Wagner, A.K.; Zhang, F.; Lu, C.Y. (2015/07) , Clinical Therapeutics, 37(7): 1420-1432 e1. [SCI]

Net Clinical Benefit of Oral Anticoagulants: A Multiple Criteria Decision Analysis

Hsu, J.C.*; Hsieh, C.Y.; Yang Kao, Y.H.; Lu, C.Y. (2015/04), PLOS One, 10(4): e0124806. [SCI]

Risk-Benefit Assessment of Oral Phosphodiesterase Type 5 Inhibitors for treatment of Erectile Dysfunction: A Multiple Criteria Decision Analysis

Hsu, J.C.*; Tang, D.H.; Lu, C.Y. (2015/04), International Journal of Clinical Practice, 69(4): 436-443. [SCI]

Utilization of Oral Antidiabetic Medications in Taiwan following Strategies to Promote Access to Medicines for Chronic Diseases in Community Pharmacies

Hsu, J.C.*; Ross-Degnan, D.; Wagner, A.K.; Cheng, C.L.; Kao Yang, Y.H.; Zhang, F. Lu, C.Y. (2015/04) , Journal of Pharmaceutical Policy and Practice, 8(1): 15-23.

The Evolution of Taiwan’s National Health Insurance Drug Reimbursement Scheme

Hsu, J.C.*; Lu, C.Y. (2015/02), DARU Journal of Pharmaceutical Sciences, 23: 15-21. [SCI]

Impacts of Drug Reimbursement Reductions on Utilization and Expenditures of Oral Antidiabetic Medications in Taiwan: An Interrupted Time Series Study

Hsu, J.C.*; Lu, C.Y.; Wagner, A.; Chan, K.W.; Lai, M.S.; Ross-Degnan, D. (2014/06), Health Policy, 116(2): 196-205. [SSCI]

Utilization Patterns of Anti-hyperuricemic Agents Following Safety Announcement on Allopurinol and Benzbromarone by Taiwan Food and Drug Administration

Cheng, C.L.; Chao, P.H.; Hsu, J.C.; Weng, M.M.Y.; On, A.W.F.; Yang Kao, Y.H.* (2014/03) , Pharmacoepidemiology and Drug Safety, 23(3): 309-313. [SCI]

A Dynamic Game Theoretic Approach on Chinese Pharmaceutical Firms’ International Strategic Alliance

Hsu, C.S.* and Wu, C.S. (2013/12), Innovation: Management, Policy & Practice, 15(3): 350-363. [SSCI]

Linking International High-tech New Ventures’ Firm Life Cycle to Internationalization, Organizational Learning, and Alliance Networks

Wu, C.S. and Hsu, C.S.* (2013/02), Journal of Enterprising Culture, 21(2):175-197. [ABI]